Inherited Genomics
What is Inherited Genomics?
Inherited genomics involves analyzing genetic variations that may have been passed down through generations. Hereditary cancer testing identifies specific genetic alterations that may increase your cancer risk.
Why Consider Hereditary Cancer Testing?
Family Risk Insight: Genetic mutations may increase cancer risk for your siblings, children, and even extended family members.
Personalized Care: Knowing your genetic makeup can guide your healthcare provider to recommend prevention and early detection strategies.
How it works
Our step-by-step approach
With concepts in hand, we meticulously design, refining every detail to align with your vision and objectives.
Common Genetic Syndromes and Their Associated Cancer Risks
| Syndrome | Cancers | Gene |
|---|---|---|
| Hereditary breast–ovarian cancer | Breast, ovarian | BRCA1/2 |
| HNPCC | Colon, endometrial, other cancers | MLH1, MSH2, MSH6 |
| Familial adenomatous polyposis | Colon, duodenum | APC |
| Cowden syndrome | Breast, thyroid | PTEN |
| Li-Fraumeni syndrome | Sarcoma, breast, brain, adrenocortical, other cancers | p53 |
| Familial melanoma | Melanoma, pancreas | CDKN2A (p16) |
| Gorlin syndrome | Basal cell carcinomas | PTCH |
| Von Hippel–Lindau syndrome | Haemangioblastoma of retina and CNS, renal cell carcinoma, phaeochromocytoma | VHL |
| Neurofibromatosis I | Neurofibrosarcoma, phaeochromocytoma, optic glioma | NF1 |
| Multiple endocrine neoplasia type 1 | Pancreatic islet, pituitary adenoma | MEN1 |
| Multiple endocrine neoplasia type 2A and 2B | Medullary thyroid carcinoma, phaeochromocytoma | RET |
| Retinoblastoma | Retinoblastoma, osteosarcoma | RB1 |